Recombinant Human Ras-Related GTP Binding C, His-tagged

• Cat.No.: RRAGC-5551H
• Product Overview: Recombinant humanRRAGC protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Ras-related GTPbinding C, also known as RRAGC, is a monomeric guanine nucleotide-bindingprotein, or G protein. By binding GTP or GDP, small G proteins act asmolecular switches in numerous cell processes and signaling pathways. RRAGChas intrinsic GTPase activity. It also regulates the organization of theactin cytoskeleton.
• Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl.
• Molecular Weight: 46.7kDa (423aa) confirmedby MALDI-TOF.
• Purity: > 85% by SDS -PAGE.
• Concentration: 0.5 mg/ml(determined by Bradford assay).
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMSLQYG AEETPLAGSY GAADSFPKDF GYGVEEEEEE AAAAGGGVGA GAGGGCGPGGADSSKPRILL MGLRRSGKSS IQKVVFHKMS PNETLFLEST NKIYKDDISN SSFVNFQIWD FPGQMDFFDPTFDYEMIFRG TGALIYVIDA QDDYMEALTR LHITVSKAYK VNPDMNFEVF IHKVDGLSDD HKIETQRDIHQRANDDLADA GLEKLHLSFY LTSIYDHSIF EAFSKVVQKL IPQLPTLENL LNIFISNSGI EKAFLFDVVSKIYIATDSSP VDMQSYELCC DMIDVVIDVS CIYGLKEDGS GSAYDKESMA IIKLNNTTVL YLKEVTKFLA LVCILREESFERKGLIDYNF HCFRKAIHEV FEVGVTSHRS CGHQTSASSL KALTHNGTPR NAI
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: RRAGC

Gene Information

• Gene Name: RRAGC Ras-related GTP binding C[ Homo sapiens ]
• Synonyms: RRAGC; Ras-relatedGTP binding C; GTR2; RAGC; ras-related GTP-binding protein C; TIB929; Rag Cprotein; GTPase-interacting protein 2
• Gene ID: 64121
• mRNA Refseq: NM_022157
• Protein Refseq: NP_071440
• MIM: 608267
• UniProt ID: Q9HB90
• Chromosome Location: 1p34
• Function: GDP binding; GTPbinding; GTPase activity; magnesium ion binding; nucleotide binding; proteinbinding; protein heterodimerization activity