Recombinant Human RANBP1
| Cat.No. : | RANBP1-30900TH |
| Product Overview : | Recombinant full length Human RanBP1 protein with an N terminal proprietary tag; predicted mwt: 49.11 kDa. |
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| Species : | Human |
| Source : | Wheat Germ |
| Tag : | Non |
| Protein Length : | 210 amino acids |
| Description : | Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. |
| Molecular Weight : | 49.110kDa |
| Form : | Liquid |
| Purity : | Proprietary Purification |
| Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : | MAAAKDTHEDHDTSTENTDESNHDPQFEPIVSLPEQEIKT LEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKH KEKGAIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAW VWNTHADFADECPKPELLAIRFLNAENAQKFKTKFEECRK EIEEREKKAGSGKNDHAEKVAEKLEALSVKEETKEDAEEK Q |
| Sequence Similarities : | Belongs to the RANBP1 family.Contains 1 RanBD1 domain. |
| Gene Name | RANBP1 RAN binding protein 1 [ Homo sapiens ] |
| Official Symbol | RANBP1 |
| Synonyms | RANBP1; RAN binding protein 1; ran-specific GTPase-activating protein; HTF9A; |
| Gene ID | 5902 |
| mRNA Refseq | NM_002882 |
| Protein Refseq | NP_002873 |
| MIM | 601180 |
| Uniprot ID | P43487 |
| Chromosome Location | 22q11.21 |
| Pathway | E2F transcription factor network, organism-specific biosystem; HIV Infection, organism-specific biosystem; HIV Life Cycle, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; |
| Function | GDP-dissociation inhibitor activity; GTPase activator activity; Ran GTPase binding; |
| ◆ Recombinant Proteins | ||
| RANBP1-3781R | Recombinant Rhesus monkey RANBP1 Protein, His-tagged | +Inquiry |
| RANBP1-12035Z | Recombinant Zebrafish RANBP1 | +Inquiry |
| RANBP1-426HF | Recombinant Full Length Human RANBP1 Protein | +Inquiry |
| RANBP1-30900TH | Recombinant Human RANBP1 | +Inquiry |
| RANBP1-1332C | Recombinant Chicken RANBP1 | +Inquiry |
| ◆ Cell & Tissue Lysates | ||
| RANBP1-2534HCL | Recombinant Human RANBP1 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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