Recombinant Human RAC2

• Cat.No.: RAC2-486H
• Product Overview: Recombinant human RAC2 was expressed inE.coliand purified by using conventional chromatography techniques. MW = 23.3 kDa (209aa).

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Rac2 is a small signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. Rac proteins play important roles in multiple cellular events, including actin cytoskeletal organization, cell proliferation and survival, cell cycle progression, and gene transcription regulation.
• Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDSKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASY ENVRAKWFPE VRHHCPSTPI ILVGTKLDLR DDKDTIEKLK EKKLAPITYP QGLALAKEID SVKYLECSAL TQRGLKTVFD EAIRAVLCPQ PTRQQKRAC.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 2mM EDTA, 2mM DTT, 0.1 M NaCl.
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) [ Homo sapiens ]
• Synonyms: RAC2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Gx; EN-7; HSPC022; ras-related C3 botulinum toxin substrate 2; small G protein; rho family, small GTP binding protein Rac2; p21-Rac2; Small G protein; GX; Ras-related C3 botulinum toxin substrate 3 (rho family,small GTP-binding protein Rac2)
• Gene ID: 5880
• mRNA Refseq: NM_002872
• Protein Refseq: NP_002863
• MIM: 602049
• UniProt ID: P15153
• Chromosome Location: 22q13.1
• Pathway: Adherens junction; Axon guidance; B cell receptor signaling pathway; Chemokine signaling pathway; Colorectal cancer; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Focal adhesion; Leukocyte transendothelial migration; MAPK signaling pathway; Natural killer cell mediated cytotoxicity; Pancreatic cancer; Pathways in cancer; Regulation of actin cytoskeleton; VEGF signaling pathway; Wnt signaling pathway; Signaling by Rho GTPases
• Function: GTP binding; GTPase activity; nucleotide binding; protein binding