Recombinant Human RAB4A, His-tagged

• Cat.No.: RAB4A-3556H
• Product Overview: Recombinant human RAB4A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography (1-218aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: RAB4A belongs to the small GTPase superfamily. RAB4A has been shown to interact with STX4, RAB11FIP1, RABEP1, CD2AP and KIF3B. Rab4 is also involved in the translocation of glucose transporter (Glu4) in adipocytes in response to insulin. Overexpression of Rab4 causes a redistribution of receptors on plasma membrane versus endocytic compartments.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT
• Molecular Weight: 26.5 kDa (238aa), confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Concentration: 1.0 mg/ml (determined by Bradford assay)
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSQTAMSETY DFLFKFLVIG NAGTGKSCLL HQFIEKKFKD DSNHTIGVEF GSKIINVGGK YVKLQIWDTA GQERFRSVTR SYYRGAAGAL LVYDITSRET YNALTNWLTD ARMLASQNIV IILCGNKKDL DADREVTFLE ASRFAQENEL MFLETSALTG ENVEEAFVQC ARKILNKIES GELDPERMGS GIQYGDAALR QLRSPRRAQA PNAQECGC.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RAB4A RAB4A, member RAS oncogene family [ Homo sapiens ]
• Official Symbol: RAB4A
• Synonyms: RAB4A; RAB4A, member RAS oncogene family; Oncogene RAB4; RAB4, member RAS oncogene family; ras-related protein Rab-4A; HRES-1/RAB4; RAB4
• Gene ID: 5867
• mRNA Refseq: NM_004578
• Protein Refseq: NP_004569
• MIM: 179511
• UniProt ID: P20338
• Chromosome Location: 1q42-q43
• Function: GDP binding; GTPase activity; ionotropic glutamate receptor binding; protein transporter activity; syntaxin binding