Recombinant Human RAB3GAP1 Protein, MYC/DDK-tagged

• Cat.No.: RAB3GAP1-304H
• Product Overview: Recombinant human RAB3GAP1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 111.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RAB3 GTPase activating protein catalytic subunit 1 [ Homo sapiens ]
• Official Symbol: RAB3GAP1
• Synonyms: P130; RAB3GAP; RAB3GAP130; WARBM1
• Gene ID: 22930
• mRNA Refseq: NM_001172435.1
• Protein Refseq: NP_001165906.1
• MIM: 602536
• UniProt ID: Q15042