Recombinant Human PZP Protein (Asn341-Ser690), N-His tagged

• Cat.No.: PZP-5459H
• Product Overview: Recombinant human PZP (Asn341-Ser690) fused with the N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Asn341-Ser690
• Description: The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 40.71 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02 % NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: PZP PZP alpha-2-macroglobulin like [ Homo sapiens (human) ]
• Official Symbol: PZP
• Synonyms: PZP; PZP alpha-2-macroglobulin like; CPAMD6; pregnancy zone protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; Pregnancy zone protein; pregnancy-zone protein
• Gene ID: 5858
• mRNA Refseq: NM_002864
• Protein Refseq: NP_002855
• MIM: 176420
• UniProt ID: P20742