Recombinant Human PUM1 Protein, MYC/DDK-tagged

• Cat.No.: PUM1-3159H
• Product Overview: Recombinant Human PUM1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 126.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PUM1 pumilio homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: PUM1
• Synonyms: HSPUM; PUMH; PUMH1; PUML1
• Gene ID: 9698
• mRNA Refseq: NM_001020658
• Protein Refseq: NP_001018494
• MIM: 607204
• UniProt ID: Q14671