Recombinant Human PTPRH Protein, MYC/DDK-tagged

• Cat.No.: PTPRH-3117H
• Product Overview: Recombinant Human PTPRH protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 122.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PTPRH protein tyrosine phosphatase, receptor type, H [ Homo sapiens ]
• Official Symbol: PTPRH
• Synonyms: R-PTP-H; SAP1
• Gene ID: 5794
• mRNA Refseq: NM_001161440
• Protein Refseq: NP_001154912
• MIM: 602510
• UniProt ID: Q9HD43