PTPRH
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Official Full Name
protein tyrosine phosphatase, receptor type, H -
Overview
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues. Alternative splicing results in multiple transcript variants. -
Synonyms
PTPRH;protein tyrosine phosphatase, receptor type, H;receptor-type tyrosine-protein phosphatase H;SAP 1;R-PTP-H;transmembrane-type protein-tyrosine phosphatase type H;stomach cancer-associated protein tyrosine phosphatase 1;SAP1;FLJ39938;MGC13305
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- His&T7
- Myc&DDK
- His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PTPRH-5697H | Recombinant Human PTPRH protein, His & T7-tagged | E.coli | Human | His&T7 | Asn844~Asp1096 |
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| Ptprh-5698M | Recombinant Mouse Ptprh protein, His & T7-tagged | E.coli | Mouse | His&T7 | Gln685~Ser909 |
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| Ptprh-5699R | Recombinant Rat Ptprh protein, His & T7-tagged | E.coli | Rat | His&T7 | Arg551~Tyr802 |
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| PTPRH-3117H | Recombinant Human PTPRH Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| PTPRH-3645H | Recombinant Human PTPRH Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Ptprh-5246M | Recombinant Mouse Ptprh Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PTPRH-6107H | Recombinant Human PTPRH Protein (Asn844-Asp1096), N-His tagged | E.coli | Human | His | Asn844-Asp1096 |
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Involved Pathway
PTPRH involved in several pathways and played different roles in them. We selected most pathways PTPRH participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPRH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PTPRH has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PTPRH itself. We selected most functions PTPRH had, and list some proteins which have the same functions with PTPRH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
PTPRH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPRH here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPRH.
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