Recombinant Human PTPN20A Protein, His-tagged

• Cat.No.: PTPN20A-382H
• Product Overview: Recombinant Human PTPN20A, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more centromeric copy, PTPN20A. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 48.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PTPN20A protein tyrosine phosphatase, non-receptor type 20A [ Homo sapiens ]
• Official Symbol: PTPN20A
• Synonyms: CT126; PTPN20B; hPTPN20; bA142I17.1
• Gene ID: 653129
• mRNA Refseq: NM_001042389
• Protein Refseq: NP_001035848
• MIM: 610630
• UniProt ID: Q4JDL3