Recombinant Human PTPN18 cell lysate
Cat.No. : | PTPN18-1437HCL |
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- Gene Information
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Species : | Human |
Tag : | Non |
Description : | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name | PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) [ Homo sapiens ] |
Official Symbol | PTPN18 |
Synonyms | BDP1; PTP-HSCF |
Gene ID | 26469 |
mRNA Refseq | NM_014369.3 |
Protein Refseq | NP_055184.2 |
MIM | 606587 |
UniProt ID | Q99952 |
Chromosome Location | 2q21.1 |
Pathway | B Cell Receptor Signaling Pathway, organism-specific biosystem; |
Function | non-membrane spanning protein tyrosine phosphatase activity; |
◆ Recombinant Proteins | ||
Ptpn18-5237M | Recombinant Mouse Ptpn18 Protein, Myc/DDK-tagged | +Inquiry |
PTPN18-2003H | Recombinant Human PTPN18 Protein, His&GST-tagged | +Inquiry |
PTPN18-6229H | Recombinant Human PTPN18 Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
PTPN18-13679M | Recombinant Mouse PTPN18 Protein | +Inquiry |
PTPN18-3132H | Recombinant Human PTPN18 Protein, MYC/DDK-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
PTPN18-1437HCL | Recombinant Human PTPN18 cell lysate | +Inquiry |
Not For Human Consumption!
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