Recombinant Human PTPN14 protein, His & GST-tagged

• Cat.No.: PTPN14-1676H
• Product Overview: Recombinant Human PTPN14 aa. (Met1~Glu189 (Accession # Q15678)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 52.3kDa
• Protein length: Met1~Glu189
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.
• Isoelectric Point: 5.8

Gene Information

• Gene Name: PTPN14 protein tyrosine phosphatase, non-receptor type 14 [ Homo sapiens (human) ]
• Official Symbol: PTPN14
• Synonyms: PTPN14; protein tyrosine phosphatase, non-receptor type 14; PEZ; PTP36; tyrosine-protein phosphatase non-receptor type 14; cytoskeletal-associated protein tyrosine phosphatase; protein-tyrosine phosphatase pez
• Gene ID: 5784
• mRNA Refseq: NM_005401.4
• Protein Refseq: NP_005392.2
• UniProt ID: Q15678