Recombinant Human PTP4A1, His-tagged

• Cat.No.: PTP4A1-952H
• Product Overview: Recombinant human PTP4A1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography.MW = 21.6 kDa (190aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: PTP4A1, also known as protein tyrosine phosphatase type IVA 1, is cell signaling molecule that plays regulatory roles in a variety of cellular processes. This protein is a unique nuclear PTP that is induced in regenerating liver and mitogen stimulated cells. It is primarily expressed in spleen, bone marrow, thymus, lymph nodes, T lymphocytes and tonsil and is overexpressed in tumor cell lines.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl, 1mM DTT.
• Purity: > 90% by SDS - PAGE.
• Concentration: 1.0 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MARMNRPAPV EVTYKNMRFL ITHNPTNATL NKFIEELKKY GVTTIVRVCE ATYDTTLVEK EGIHVLDWPF DDGAPPSNQI VDDWLSLVKI KFREEPGCCI AVHCVAGLGR APVLVALALI EGGMKYEDAV QFIRQKRRGA FNSKQLLYLE KYRPKMRLRF KDSNGHRNNC.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PTP4A1 protein tyrosine phosphatase type IVA, member 1 [ Homo sapiens ]
• Synonyms: protein tyrosine phosphatase type IVA, member 1; HH72; PRL1; PRL-1; PTPCAAX1; PTP(CAAX1); DKFZp779M0721; PTP4A1; protein tyrosine phosphatase type IVA 1; PTP(CAAXI); protein-tyrosine phosphatase 4a1; Protein tyrosine phosphatase IVA1; protein tyrosine phosphatase type IVA protein 1; protein-tyrosine phosphatase of regenerating liver 1; Protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; EC 3.1.3.48
• Gene ID: 7803
• mRNA Refseq: NM_003463
• Protein Refseq: NP_003454
• MIM: 601585
• UniProt ID: Q93096
• Chromosome Location: 6q12
• Function: protein tyrosine phosphatase activity; hydrolase activity