Recombinant Human PTEN Protein, His-tagged

• Cat.No.: PTEN-663H
• Product Overview: Recombinant Human PTEN fused with His tag at N-terminal was expressed in Sf9 cells.

Specification

• Description: Isoform alpha: Functional kinase, like isoform 1 it antagonizes the PI3K-AKT/PKB signaling pathway. Plays a role in mitochondrial energetic metabolism by promoting COX activity and ATP production, via collaboration with isoform 1 in increasing protein levels of PINK1.
• Source: Sf9 cells
• Species: Human
• Tag: His
• Form: 50mM Tris-HCl pH8.0, 150mM NaCl, 20% glycerol. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 47 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PTEN phosphatase and tensin homolog [ Homo sapiens ]
• Official Symbol: PTEN
• Synonyms: PTEN; phosphatase and tensin homolog; BZS, MHAM; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; MMAC1; mutated in multiple advanced cancers 1; PTEN1; TEP1; phosphatase and tensin-like protein; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; BZS; DEC; GLM2; MHAM; 10q23del; MGC11227
• Gene ID: 5728
• mRNA Refseq: NM_000314
• Protein Refseq: NP_000305
• UniProt ID: P60484