Recombinant Human PTBP2 protein, Full Length, N-His tagged

• Cat.No.: PTBP2-83HFL
• Product Overview: Recombinant Full Length Human PTBP2 protein with N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: Full Length
• Description: The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 58 kDa
• AA Sequence: MHHHHHHHHHHDGIVTEVAVGVKRGSDELLSGSVLSSPNSNMSSMVVTANGNDSKKFKGEDKMDGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQAVLQAVTAVQTANTPLSGTTVSESAVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAGRVGMPGVSAGGNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI
• Purity: > 95% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 7 mg/mL by BCA
• Storage Buffer: Sterile 50mM Tris, 300mM NaCl, 1mM EDTA, pH 7.6

Gene Information

• Gene Name: PTBP2 polypyrimidine tract binding protein 2 [ Homo sapiens (human) ]
• Official Symbol: PTBP2
• Synonyms: PTBP2; polypyrimidine tract binding protein 2; nPTB; PTBLP; brPTB; polypyrimidine tract-binding protein 2; PTB-like protein; neural polypyrimidine tract binding protein; neurally-enriched homolog of PTB
• Gene ID: 58155
• mRNA Refseq: NM_021190
• Protein Refseq: NP_067013
• MIM: 608449
• UniProt ID: Q9UKA9