Recombinant Human PSMA8, His-tagged

• Cat.No.: PSMA8-30593TH
• Product Overview: Recombinant full length Human PSMA8, isoform 3 (1-250 amino acids) with N-terminal His tag;270 aa, predicted MW 30kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 250 amino acids
• Description: PSMA8 is a protease which cleaves peptide bonds with broad specificity.
• Conjugation: HIS
• Molecular Weight: 30.000kDa inclusive of tags
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:10% Glycerol, 0.32% Tris HCl, 0.02% DTT, 0.58% Sodium chloride
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MASRYDRAIT VFSPDGHLFQ VEYAQEAVKK GSTAVGIRGT NIVVLGVEKK SVAKLQDERT VRKICALDDH VCMAFAGLTA DARVVINRAR VECQSHKLTV EDPVTVEYIT RFIATLKQKY TQSNGRRPFG ISALIVGFDD DGISRLYQTD PSGTYHAWKANAIGRSAKTV REFLEKNYTE DAIASDSEAI KLAIKALLEV VQSGGKNIEL AIIRRNQPLK MFSAKEVELY VTEIEKEKEE AEKKKSKKSV
• Sequence Similarities: Belongs to the peptidase T1A family.

Gene Information

• Gene Name: PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 [ Homo sapiens ]
• Official Symbol: PSMA8
• Synonyms: PSMA8; proteasome (prosome, macropain) subunit, alpha type, 8; proteasome subunit alpha type-7-like; MGC26605; PSMA7L
• Gene ID: 143471
• mRNA Refseq: NM_144662
• Protein Refseq: NP_653263
• Uniprot ID: Q8TAA3
• Chromosome Location: 18q11.2
• Pathway: APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem
• Function: peptidase activity; threonine-type endopeptidase activity