Recombinant Human PSMA5 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PSMA5-4060H
• Product Overview: PSMA5 MS Standard C13 and N15-labeled recombinant protein (NP_002781) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.
• Molecular Mass: 26.2 kDa
• AA Sequence: MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKDITRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PSMA5 proteasome 20S subunit alpha 5 [ Homo sapiens (human) ]
• Official Symbol: PSMA5
• Synonyms: PSMA5; proteasome (prosome, macropain) subunit, alpha type, 5; proteasome subunit alpha type-5; ZETA; macropain zeta chain; proteasome zeta chain; macropain subunit zeta; proteasome component 5; proteasome subunit zeta; proteasome alpha 5 subunit; multicatalytic endopeptidase complex zeta chain; PSC5; FLJ42315; MGC117302; MGC125802; MGC125803; MGC125804
• Gene ID: 5686
• mRNA Refseq: NM_002790
• Protein Refseq: NP_002781
• MIM: 176844
• UniProt ID: P28066