Recombinant Human PRPF6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PRPF6-3647H
• Product Overview: PRPF6 MS Standard C13 and N15-labeled recombinant protein (NP_036601) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.
• Molecular Mass: 106.9 kDa
• AA Sequence: MNKKKKPFLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQMKKNQAADDDDEDLNDTNYDEFNGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERREQREKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRYEKLTPVPDSFFAKHLQTGENHTSVDPRQTQFGGLNTPYPGGLNTPYPGGMTPGLMTPGTGELDMRKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTHGGDINDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPEDARIMLSRAVECCPTSVELWLALARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTFTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PRPF6 pre-mRNA processing factor 6 [ Homo sapiens (human) ]
• Official Symbol: PRPF6
• Synonyms: PRPF6; PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae); C20orf14, chromosome 20 open reading frame 14, PRP6 pre mRNA processing factor 6 homolog (yeast); pre-mRNA-processing factor 6; ANT 1; bB152O15.1; Prp6; TOM; U5 102K; PRP6 homolog; U5-102 kDa protein; U5 snRNP-associated 102 kDa protein; androgen receptor N-terminal domain transactivating protein-1; androgen receptor N-terminal domain-transactivating protein 1; putative mitochondrial outer membrane protein import receptor; p102 U5 small nuclear ribonucleoprotein particle-binding protein; ANT1; ANT-1; hPrp6; U5-102K; C20orf14
• Gene ID: 24148
• mRNA Refseq: NM_012469
• Protein Refseq: NP_036601
• MIM: 613979
• UniProt ID: O94906