Recombinant Human Protein Kinase N1, GST-tagged
Cat.No. : | PKN1-1289H |
Product Overview : | Recombinant humanfull length PKN1, GST-tagged. |
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Species : | Human |
Source : | Insect Cells |
Tag : | GST |
Description : | PKN1 belongs to theprotein kinase C superfamily. This kinase is activated by the Rho family ofsmall G proteins and may mediate the Rho-dependent signaling pathway. This kinasecan also be activated by phospholipids. No special measures were taken toactivate this kinase. |
Form : | Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol |
Molecular Weight : | 132.1 kDa |
Storage : | Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | PKN1 |
Full Length : | Full L. |
Gene Name | PKN1 protein kinase N1 [ Homosapiens ] |
Synonyms | PKN1; protein kinaseN1; DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; MGC46204; PKN-ALPHA;serine/threonine-protein kinase N1; OTTHUMP00000037582; OTTHUMP00000037583;protein kinase C-like 1; protein kinase PKN-alpha; protein kinase C-like PKN;serine-threonine kinase N; protease-activated kinase 1; protein kinaseC-related kinase 1; protein-kinase C-related kinase 1; serine-threonineprotein kinase N; serine/threonine protein kinase N; EC 2.7.11.13 |
Gene ID | 5585 |
mRNA Refseq | NM_213560 |
Protein Refseq | NP_998725 |
MIM | 601032 |
UniProt ID | Q16512 |
Chromosome Location | 19p13.12 |
Pathway | G13 SignalingPathway; Regulation of Androgen receptor activity; RhoA signaling pathway;Salmonella infection; Signaling mediated by p38-gamma and p38-delta;TNF-alpha/NF-kB Signaling Pathway |
Function | ATP binding; GTP-Rhobinding; Rac GTPase binding; androgen receptor binding; chromatin binding;histone binding; histone deacetylase binding; histone kinase activity (H3-T11specific); ligand-dependent nuclear receptor transcription coactivatoractivity; nucleotide binding; protein binding; protein kinase C activity;protein kinase C binding; protein kinase activity; protein serine/threoninekinase activity |
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◆ Cell & Tissue Lysates | ||
PKN1-1363HCL | Recombinant Human PKN1 cell lysate | +Inquiry |
Not For Human Consumption!
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