Recombinant Human Protein Kinase C, Beta, GST-tagged, Active

• Cat.No.: PRKCB-400H
• Product Overview: Recombinant human full-length PKCbeta II was expressed by baculovirus inSf9 cellsusing an N-terminal GST tag. MW=105 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: PKCβ II is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol and phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. PKCβ II has been reported to be involved in many different cellular functions such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: PRKCB protein kinase C, beta [ Homo sapiens ]
• Synonyms: PRKCB; protein kinase C, beta; PKCB; PRKCB1; PRKCB2; MGC41878; PKC-beta; Protein kinase C beta type; EC 2.7.11.13; PKC-B; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide
• Gene ID: 5579
• mRNA Refseq: NM_002738
• Protein Refseq: NP_002729
• UniProt ID: P05771
• Chromosome Location: 16p12
• MIM: 176970
• Pathway: B cell receptor signaling pathway; Calcium signaling pathway; Chemokine signaling pathway; ErbB signaling pathway; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Focal adhesion; Glioma; GnRH signaling pathway; Leukocyte transendothelial migration; Long-term depression; Long-term potentiation; Non-small cell lung cancer; Pathways in cancer; Phosphatidylinositol signaling system; Tight junction; VEGF signaling pathway; Vascular smooth muscle contraction; Vibrio cholerae infection; Wnt signaling pathway; Hemostasis; Synaptic Transmission
• Function: ATP binding; calcium ion binding; nucleotide binding; protein binding; protein kinase C activity; transferase activity; zinc ion binding