PRKCB
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Official Full Name
protein kinase C, beta -
Overview
plays a role in hexosamine biosynthesis pathway induced transcriptional regulation -
Synonyms
Prkcb;protein kinase C, beta;Pkcb;Prkcb1;protein kinase C beta type;PKC-beta;protein kinase C beta I;protein kinase C beta
Recombinant Proteins
- Human
- Mouse
- Rat
- Rabbit
- Rhesus macaque
- E.coli
- Sf9 Insect Cell
- Mammalian Cell
- Insect Cell
- HEK293
- Mammalian cells
- HEK293T
- GST
- His
- His&S
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PRKCB involved in several pathways and played different roles in them. We selected most pathways PRKCB participated on our site, such as MAPK signaling pathway,ErbB signaling pathway,Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKCB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inflammatory mediator regulation of TRP channels | IL1RAP,HRH1,PRKCD,TRPV1,CYP2J6,PRKACB,TRPM8,ASIC4,CYP2C37,ACCN4 |
| African trypanosomiasis | PLCB2,HBA-A2,HBB-B1,VCAM1,SELE,IL6,PLCB3,MYD88,IFNG,Fasl |
| Focal adhesion | FLNA,ARHGAP35,PARVG,THBS4B,TLN1,PIK3R3,CAV1,CAPN2A,PDGFB,PAK1 |
| Non-small cell lung cancer | TGFA,RASSF1,RAF1,FOXO3,STK4,NRAS,RXRA,PLCG2,CCND1,PIK3R1 |
| Fc gamma R-mediated phagocytosis | RPS6KB2,VASP,ASAP3,PTPRC,AKT1,PIK3CG,ASAP2,LIMK2,PLD2,WASF2 |
| Insulin secretion | SLC2A1,CAMK2D,GCG,CCKAR,PRKACA,ATF4,CAMK2G,KCNMB3,KCNMB2,CAMK2A |
| Thyroid hormone synthesis | ATF4,ASGR1,CANX,PAX8,LRP2,SLC5A5,TG,HSPA5,HSP90B1,CREB3L1 |
| Gap junction | TUBB2B,PDGFRB,TUBA1B,GRB2A,TUBA8L4,TJP1,RAF1,PRKACBA,TUBB6,ADCY1A |
| Hepatitis B | MAPK9,GRB2,STAT6,CCNA2,MAPK1,PCNA,MYD88,MAPK8,CASP12,MAP2K1 |
Protein Function
PRKCB has several biochemical functions, for example, ATP binding,androgen receptor binding,calcium channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKCB itself. We selected most functions PRKCB had, and list some proteins which have the same functions with PRKCB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase C activity | PRKCZ,PRKCD,PRKCDA,PRKD3,PRKCG,PRKCI,PRKCBB,PRKCHB,PRKCQ,PRKCE |
| calcium channel regulator activity | NRXN1,PRKG1,CACNA2D2,TSPAN13B,NRXN3,TSPAN13A,CAV3,SGK1,TMEM110,SGK3 |
| ATP binding | PLK5,FRK,ENTPD2,PRKCQ,YTHDC2,NMNAT1,TXK,CDC42BPA,SYN3,SRPK2 |
| protein serine/threonine kinase activity | STK19,STRC,CSNK1DA,BRAF,PRKCZ,STK16,GRK5,PIK3CA,MOK,HIPK4 |
| histone kinase activity (H3-T6 specific) | PRKCBB,PRKCA |
| protein kinase C binding | GLRX3,HAND2,PAWR,TIRAP,LDB3,NELL2,DSP,UGT1A7,AKT1,GRK5 |
| zinc ion binding | SH3RF1,CPA3,RNFT1,ING5,RBX1,PAM,CRIP1,ATXN7L3,VAT1,MDM4 |
| chromatin binding | SFPQ,TFAP2A,CREB3L1,DNMT1,ING5,TCF7L1B,SUV39H1,RDBP,BCL6,SP110 |
| histone binding | ANP32B,HIST1H3I,ANP32E,MYSM1,NAP1L2,HJURP,DNAJC2,DEK,ELP2,NFKBIL2 |
Interacting Protein
PRKCB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKCB here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKCB.
TINF2;N/A;Glrb;PRL1;IKBKB;CHUK;LYN;HSP90AB1;GSK3B;GNB2L1;SHCBP1;PAG1;AKT1;TERF1;amn;bosutinib;bisindolylmaleimide iii;imatinib
Resources
Research Area
Histone PhosphorylationIntracellular Kinases in the Akt Pathway
PKC Isoforms
Wnt Intracellular Signaling
Intracellular Signaling Molecules in Angiogenesis
PKC Family
Related Services
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References
