Recombinant Human Prostaglandin E Synthase 2, His-tagged

• Cat.No.: PTGES2-993H
• Product Overview: Recombinant human PTGES2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-186aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: PTGES2 is a membrane-associatedprostaglandin E synthase, which catalyzes the conversion ofprostaglandin H2 to prostaglandin E2. This protein also has beenshown to activate the transcription regulated by agamma-interferon-activated transcription element.
• Form: 23.5 kDa (206aa), confirmed by MALDI-TOF
• Molecular Weight: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 2mM DTT, 0.2M NaCl.
• Purity: > 95 % by SDS - PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MKAVNEQGKE VTEFGNKYWL MLNEKEAQQV YGGKEARTEE MKWRQWADDW LVHLISPNVY RTPTEALASF DYIVREGKFG AVEGAVAKYM GAAAMYLISK RLKSRHRLQD NVREDLYEAA DKWVAAVGKD RPFMGGQKPN LADLAVYGVL RVMEGLDAFD DLMQHTHIQP WYLRVERAIT EASPAH
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PTGES2 prostaglandin E synthase 2 [ Homosapiens ]
• Synonyms: PTGES2; GBF1; PGES2; C9orf15; mPGES-2; FLJ14038; MGC11289; prostaglandin E synthase 2; OTTHUMP00000022232; OTTHUMP00000215363; GATE-binding factor 1; microsomal prostaglandin E synthase 2; microsomal prostaglandin E synthase-2; membrane-associated prostaglandin E synthase 2; gamma-interferon-activated transcriptional element-binding factor 1; NP_079348.1; EC 5.3.99.3
• Gene ID: 80142
• mRNA Refseq: NM_025072
• Protein Refseq: NP_079348
• MIM: 608152
• UniProt ID: Q9H7Z7
• Chromosome Location: 9q34.11
• Function: DNA binding; electron carrier activity; isomerase activity; prostaglandin-E synthase activity; protein binding; protein disulfide oxidoreductase activity; transcription activator activity