PTGES2

  • Official Full Name

    prostaglandin E synthase 2

  • Overview

    The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.

  • Synonyms

    PTGES2;prostaglandin E synthase 2;C9orf15, chromosome 9 open reading frame 15;FLJ14038;C9orf15;Gamma interferon activated transcriptional element binding factor 1;GATE binding factor 1;GBF1;Membrane associated prostaglandin E synthase 2;MGC11289;Microsomal prostaglandin E synthase 2;mPGES 2;mPGES-2;PGES2;PGES2_HUMAN;Prostaglandin E synthase 2 truncated form;PTGES 2;OTTHUMP00000022231;OTTHUMP00000022232;OTTHUMP00000215363;GATE-binding factor 1;microsomal prostaglandin E synthase-2;membrane-associated prostaglandin E synthase 2;gamma-interferon-activated

Recombinant Proteins

  • Human
  • Mouse
  • Cynomolgus
  • zebrafish
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • His&T7
  • Non
  • Avi&Fc&His
Cat.# Product name Source (Host) Species Tag Protein Length Price
PTGES2-2045H Recombinant Human PTGES2, GST-tagged E.coli Human GST 1-377aa
PTGES2-13641M Recombinant Mouse PTGES2 Protein Mammalian Cells Mouse His
PTGES2-30326TH Recombinant Human PTGES2, His-tagged E.coli Human His 206 amino acids
PTGES2-5623H Recombinant Human PTGES2 protein, His & T7-tagged E.coli Human His&T7 Tyr145~Thr357
Ptges2-5624M Recombinant Mouse Ptges2 protein, His-tagged E.coli Mouse His Tyr144~Asp384
PTGES2-828C Recombinant Cynomolgus PTGES2 Protein, His-tagged Mammalian Cells Cynomolgus His
PTGES2-993H Recombinant Human Prostaglandin E Synthase 2, His-tagged E.coli Human His
PTGES2-2713HCL Recombinant Human PTGES2 293 Cell Lysate HEK293 Human Non
PTGES2-2714HCL Recombinant Human PTGES2 293 Cell Lysate HEK293 Human Non
PTGES2-571C Recombinant Cynomolgus Monkey PTGES2 Protein, His (Fc)-Avi-tagged HEK293 Cynomolgus Avi&Fc&His
PTGES2-571C-B Recombinant Cynomolgus Monkey PTGES2 Protein Pre-coupled Magnetic Beads HEK293 Cynomolgus
PTGES2-6602H Recombinant Human PTGES2 Protein (Tyr145-Thr357), N-His tagged E.coli Human His Tyr145-Thr357
PTGES2-7253M Recombinant Mouse PTGES2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
PTGES2-7253M-B Recombinant Mouse PTGES2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
RFL26151DF Recombinant Full Length Danio Rerio Prostaglandin E Synthase 2(Ptges2) Protein, His-Tagged E.coli zebrafish His Full L. Full Length (1-377)

    Involved Pathway

    PTGES2 involved in several pathways and played different roles in them. We selected most pathways PTGES2 participated on our site, such as Arachidonic acid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTGES2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways ETNK1,HLCS,AMPD1,ST3GAL3B,UPP1,AGPAT9L,PLD1A,ALG5,LDHAL6A,BCAT1
    Arachidonic acid metabolism CBR1,GGTLC1,PLA2G4AA,CBR3,ALOX12,AWAT2,CYP2Y3,CYP2C37,HPGDS,CYP1A1

    Protein Function

    PTGES2 has several biochemical functions, for example, DNA binding,electron carrier activity,glutathione binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTGES2 itself. We selected most functions PTGES2 had, and list some proteins which have the same functions with PTGES2. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding ENG2B,TEAD4,SSH2B,PPP1R10,ZNF207,SCML2,CERS4A,FOXP3A,ZNF280B,RNF4
    lyase activity ALDOCA,HOGA1,CAR6,ENO1A,PDXDC1,MVDA,Car4,PTGESL,Car14,CTHL
    protein binding EID1,IGFBP5,XPO5,HAT1,ZHX3,PHF21A,TNKS2,TMBIM6,TRA2B,TUBA1A
    electron carrier activity ME1,DHRS3,CYCSB,GCDH,AOX1,ASPH,GLRX3,GRXCR1,ACADL,FDX1B
    prostaglandin-E synthase activity PTGES,PTGESL,PTGES3
    heme binding DGCR8,CYP1A1,CYP11A1,CYP2C55,NOX4,CYP7B1,LPO,CYP19A1B,CYP3C1,CYP4A11
    protein disulfide oxidoreductase activity DNAJC10,ERO1L,GRX2,GLRX2,ENOX2,TXN,TXNL1,SH3BGRL3,CCS,GLRX5
    glutathione binding GSTM1,PTGESL,GPX1,LTC4S,PTGES,GSTP2,GSTM2,GSTM3,MGST1,GSS

    Interacting Protein

    PTGES2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTGES2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTGES2.

    C1orf189;HTT;EXOSC10;uvrB;MYC;1C;H2AFX

    Resources

    Research Area

    Neuroinflammation
    Neurotransmitter Associated Enzymes
    Prostaglandin Synthases
    MDSC Cytokines and Growth Factors

    References

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