Recombinant Human Progesterone receptor LBD/Hsp90 complex, GST-tagged

• Cat.No.: PGR-106H
• Product Overview: Recombinant Human GST-tagged Progesterone receptor ligand-binding domain (PR-LBD) consists of a 218 a.a. GST tag, a 31 a.a. flexible linker and a 305 a.a. PR-LBD, Acc# NP_000917, amino acids 630-933. A complex of human PR-LBD with human Hsp90 (PR-LBD/Hsp90) was produced in insect cells co-infected with two recombinant baculoviruses. GST tagged PR-LBD and Hsp90 are the major components of the complex.

Specification

• Source: Sf9 insect cells
• Species: Human
• Tag: GST
• Form: 20 mM Na-P pH 8.0, 40 mM KCl, 20 mM Na2MoO4, 5 mM DTT, 7 mM reduced glutathione, 15% glycerol.
• Purity: >80%
• Applications: Ligand binding and coactivator peptide recruitment assays.
• Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.

Gene Information

• Gene Name: PGR progesterone receptor [ Homo sapiens ]
• Official Symbol: PGR
• Synonyms: PGR; progesterone receptor; NR3C3; PR; nuclear receptor subfamily 3 group C member 3
• Gene ID: 5241
• mRNA Refseq: NM_000926
• Protein Refseq: NP_000917
• MIM: 607311
• UniProt ID: P06401
• Chromosome Location: 11q22-q23
• Pathway: Cellular roles of Anthrax toxin, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; Oocyte meiosis, organism-specific biosystem
• Function: DNA binding; enzyme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding