Recombinant Human PROCR protein, His-tagged

• Cat.No.: PROCR-589H
• Product Overview: Recombinant Human PROCR (Q9UNN8) aa. (Thr63~Ser205) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Thr63~Ser205
• Description: The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 17.6kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Characteristic: The isoelectric point is 6.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4

Gene Information

• Gene Name: PROCR protein C receptor [ Homo sapiens (human) ]
• Official Symbol: PROCR
• Synonyms: PROCR; protein C receptor; CCCA; EPCR; CCD41; endothelial protein C receptor; APC receptor; CD201 antigen; activated protein C receptor; cell cycle, centrosome-associated protein; centrocyclin; protein C receptor, endothelial
• Gene ID: 10544
• mRNA Refseq: NM_006404.4
• Protein Refseq: NP_006395.2
• UniProt ID: Q9UNN8