Recombinant Human PROCR, His-tagged

• Cat.No.: PROCR-145H
• Product Overview: PROCR, 18-210aa, Human, His tag, E.coli

Specification

• Description: PROCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. This protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. Recombinant human PROCR protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 24.4 kDa (216aa)
• Protein length: 18-210aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSQDASDG LQRLHMLQIS YFRDPYHVWY QGNASLGGHL THVLEGPDTN TTIIQLQPLQ EPESWARTQS GLQSYLLQFH GLVRLVHQER TLAFPLTIRC FLGCELPPEG SRAHVFFEVA VNGSSFVSFR PERALWQADT QVTSGVVTFT LQQLNAYNRT RYELREFLED TCVQYVQKHI SAENTKGSQT SRSYTS
• Purity: >80% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: PROCR protein C receptor, endothelial [ Homo sapiens ]
• Official Symbol: PROCR
• Synonyms: PROCR; protein C receptor, endothelial; endothelial protein C receptor; CCD41; CD201; EPCR; APC receptor; centrocyclin; CD201 antigen; activated protein C receptor; endothelial cell protein C receptor; cell cycle, centrosome-associated protein; CCCA; bA42O4.2; MGC23024
• Gene ID: 10544
• mRNA Refseq: NM_006404
• Protein Refseq: NP_006395
• MIM: 600646
• UniProt ID: Q9UNN8
• Chromosome Location: 20q11.2
• Function: protein binding; receptor activity