Recombinant Human Pro-Platelet Basic Protein (chemokine (C-X-C motif) ligand 7)

• Cat.No.: PPBP-339H

Specification

• Species: Human
• Source: Human
• Tag: Non
• Protein Length: 35-128 a.a.
• ProductOverview: Recombinanthuman PPBP protein was expressed in E. coli and purified by usingconventional chromatograph.
• Description: PPBP, also known aschemokine (C-X-C motif) ligand 7 (CXCL7), is a platelet-derived growth factorthat belongs to the alpha-chemokine family, It is a protein that is releasedin large amounts from platelets following their activation. It stimulatesvarious processes including mitogenesis, synthesis of extracellular matrix,glucose metabolism and synthesis of plasminogen activator.
• Concentration: 1mg/ml
• Form: Supplied as a liquidin 20mM Tris-HCl buffer, pH 7.5, containing 10% glycerol and 1mM DTT.
• Purity: >90% by SDS - PAGE
• Sequence: 35-128amino acids: MSSTKGQTKR NLAKGKEESL DSDLYAELRC MCIKTTSGIH PKNIQSLEVIGKGTHCNQVE VIATLKDGRK ICLDPDAPRI KKIVQKKLAG DESAD
• MolecularMass: 10.3 kDa (95aa),confirmed by MALDI-TOF.
• Applications: SDS-PAGE
• Storage: Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: PPBP

Gene Information

• Gene Name: PPBP pro-platelet basic protein(chemokine (C-X-C motif) ligand 7) [ Homo sapiens ]
• Synonyms: PPBP; pro-plateletbasic protein (chemokine (C-X-C motif) ligand 7); PBP; TC1; TC2; TGB; LDGF;MDGF; TGB1; B-TG1; CTAP3; CXCL7; NAP-2; SCYB7; THBGB; LA-PF4; SCAR10; THBGB1;Beta-TG; CTAPIII; CTAP-III; PPBP; platelet basic protein; thrombocidin 1;thrombocidin 2; OTTHUMP00000160477; b-TG1; NAP-2-L1; beta-thromboglobulin;CXC chemokine ligand 7; C-X-C motif chemokine 7; thromboglobulin, beta-1;small inducible cytokine B7; small-inducible cytokine B7; leukocyte-derivedgrowth factor; low-affinity platelet factor IV; neutrophil-activating peptide2; neutrophil-activating peptide-2; macropha- ge-derived growth factor;connective tissue-activating peptide III; small inducible cytokine subfamilyB, member 7; Macrophage-derived growth factor; Small-inducible cytokine B7;Leukocyte-derived growth factor
• Gene ID: 5473
• mRNA Refseq: NM_002704
• Protein Refseq: NP_002695
• MIM: 121010
• UniProt ID: P02775
• Chromosome Location: 4q12-q13
• Pathway: Chemokinereceptors bind chemokines; Chemokine signaling pathway; Class A/1(Rhodopsin-like receptors); Cytokine-cytokine receptor interaction
• Function: chemokine activity;glucose transmembrane transporter activity; growth factor activity