Recombinant Human PRKY, GST-tagged

• Cat.No.: PRKY-829H
• Product Overview: Recombinant human PRKY (40-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• ProteinLength: 40-end
• Description: PRKY or protein kinase, Y-linked, pseudogene is a novel serine/threonine subtype of protein kinase that appears to encode a protein related to the catalytic subunit of the cAMP-dependent protein kinases which are key players in the cellular responses to the second messenger cAMP. PRKY gene is classified as a transcribed pseudogene because it has lost a coding exon that results in all transcripts being candidates for nonsense-mediated decay (NMD) and unlikely to express a protein. Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females.
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~53 kDa
• Purity: >75%
• Applications: Western Blot
• Stability: 1yr at –70°C from date of shipment
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1ug/ul

Gene Information

• Gene Name: PRKY protein kinase, Y-linked, pseudogene [ Homo sapiens ]
• Official Symbol: PRKY
• Synonyms: PRKY; protein kinase, Y-linked, pseudogene; PRKYP; PRKXP3; protein kinase, Y-linked; EC 2.7.11.1; EC 2.7.11; Serine/threonine protein kinase PRKY
• Gene ID: 5616
• mRNA Refseq: NM_002760
• MIM: 400008
• UniProt ID: O43930
• Chromosome Location: Yp11.2
• Function: ATP binding; protein serine/threonine kinase activity