Recombinant Human PRKCE Protein, DDK-tagged

• Cat.No.: PRKCE-657H
• Product Overview: Recombinant Human PRKCE fused with DDK tag at C-terminal was expressed in Sf9 cells.

Specification

• Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.
• Source: Sf9 cells
• Species: Human
• Tag: Flag
• Form: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
• Molecular Mass: 83.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PRKCE protein kinase C, epsilon [ Homo sapiens ]
• Official Symbol: PRKCE
• Synonyms: PRKCE; protein kinase C, epsilon; protein kinase C epsilon type; PKCE; nPKC-epsilon; MGC125656; MGC125657
• Gene ID: 5581
• mRNA Refseq: NM_005400
• Protein Refseq: NP_005391
• MIM: 176975
• UniProt ID: Q02156