PRKCE
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Official Full Name
PRKCE protein kinase C, epsilon -
Synonyms
PRKCE;protein kinase C, epsilon;protein kinase C epsilon type;PKCE;nPKC-epsilon;MGC125656;MGC125657
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cell
- Sf9 Insect Cell
- HEK293
- Insect Cell
- Insect (sf21)
- HEK293T
- Mammalian cells
- GST
- Non
- His
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PRKCE involved in several pathways and played different roles in them. We selected most pathways PRKCE participated on our site, such as cGMP-PKG signaling pathway,Sphingolipid signaling pathway,Vascular smooth muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKCE were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Sphingolipid signaling pathway | NRAS,GNA12,BAX,PLCB1,RAC1,SPTLC2,MAPK3,MAP2K1,MAPK12,PPP2R3A |
| MicroRNAs in cancer | CYP24A1,RPTOR,TIMP3,BRCA1,PRKCB,MMP16,Abcb1b,CDC25C,SOX4,CCND1 |
| Insulin resistance | AKT2,RPS6KA1,SREBF1,G6PCA.2,PPP1CA,PRKAB1A,CREB5,MGEA5,PIK3R1,PPP1R3CA |
| Fc gamma R-mediated phagocytosis | VAV1,PIK3CB,PRKCB,PPAP2A,SPHK2,PLA2G4A,PLCG1,PIP5K1B,MARCKS,WASL |
| Type II diabetes mellitus | HK3,SLC2A4,TNF,MTOR,INS,PIK3R3,IKBKB,PIK3CA,IRS1,PDX1 |
| Tight junction | ACTN4,MYH11A,PPP2R2D,JAM2,CRB3A,CLDN5B,CLDN11A,ACTB1,RHOA,MYH13 |
| cGMP-PKG signaling pathway | MAPK3,ROCK2,GTF2IRD1,PPP1CA,NOS3,MAP2K2,MAPK1,PIK3CG,RAF1,MYLK3 |
| Inflammatory mediator regulation of TRP channels | Adcy4,CALML5,CAMK2D,CALM1,PRKACA,PRKCQ,PLCB4,CYP2C70,CALM3,PIK3CB |
| Vascular smooth muscle contraction | ADCY2B,GNA12,PLCB4,MYL6,GUCY1A3,RHOAD,CYP4A14,ADCY1A,PRKCHA,GNA11B |
Protein Function
PRKCE has several biochemical functions, for example, 14-3-3 protein binding,ATP binding,actin monomer binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKCE itself. We selected most functions PRKCE had, and list some proteins which have the same functions with PRKCE. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor activator activity | IGF2,PPARGC1B |
| protein serine/threonine kinase activity | MKNK1,CSNK1G3,ULK4,TNIK,SMOK2B,CAMK2G1,DCLK3,HIPK1,PDIK1L,CLK4 |
| 14-3-3 protein binding | ARRB2,SRPK2,AANAT,RPTOR,YWHAQ,AKT1,ZFP36,KIF13B,KCNH1,PRKCZ |
| metal ion binding | BCL11B,SMYD1A,ITGB1BP3,SEMG1,MAP3K4,Car4,CLCA5,TESK1,NR1D2A,PRUNE |
| signal transducer activity | MIER1B,APOL3,STAT5B,FPR3,GRM8B,ADRB3A,RASGRP3,GPR141,TRAF3,IL1RAP |
| enzyme activator activity | TAB1,ALOX5AP,GM1679,GTF3C4,CLPS,MMP17,MMP24,RAB3GAP2,DCP1B,UBA2 |
| enzyme binding | Il6ra,BACE1,ADORA2A,DYM,IQCB1,SUDS3,KAT8,PLCB1,UGT1A6A,DDC |
| ethanol binding | ADH4,ADH7,ADH1 |
| actin monomer binding | PFN4,MYL2,TWF1,LMOD3,TMSB10,TMSB4X,PKNOX2,COBL,PFN2,KLHL8 |
Interacting Protein
PRKCE has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKCE here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKCE.
YWHAZ;HSP90AB1;saicar;PKM;PECAM1;N/A;UGT1A7;IL32;BRAF;PRKCA;BAX;RPS6KA2;MAP4K4
Resources
Research Area
Intracellular Kinases in the Akt PathwayPKC Isoforms
Wnt Intracellular Signaling
Intracellular Signaling Molecules in Angiogenesis
PKC Family
Related Services
Related Products
References
