Recombinant Human PRDX5

• Cat.No.: PRDX5-30762TH
• Product Overview: Recombinant full length Human Peroxiredoxin 5; amino acids 53-214, 17kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 53-214 a.a.
• Description: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene.
• Tissue specificity: Widely expressed.
• Biological activity: Specific activity : 2.12 U/mgOne unit will cause the oxidation of 1μmole of NADPH at 25°C at pH 7.5.
• Form: Lyophilised:Packaging size : 0.5 mg
• Storage buffer: Preservative: NoneConstituents: 20mM HEPES, pH 7.4
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the peroxiredoxin 2 family.Contains 1 thioredoxin domain.
• Full Length: Full L.

Gene Information

• Gene Name: PRDX5 peroxiredoxin 5 [ Homo sapiens ]
• Official Symbol: PRDX5
• Synonyms: PRDX5; peroxiredoxin 5; peroxiredoxin-5, mitochondrial; ACR1; Alu co repressor 1; antioxidant enzyme B166; AOEB166; B166; liver tissue 2D page spot 71B; MGC117264; MGC142283; MGC142285; peroxisomal antioxidant enzyme; PLP; PMP20; PRDX6; PRXV; SBBI10; thio
• Gene ID: 25824
• mRNA Refseq: NM_012094
• Protein Refseq: NP_036226
• MIM: 606583
• Uniprot ID: P30044
• Chromosome Location: 11q13
• Pathway: Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem; Selenium Pathway, organism-specific biosystem
• Function: cysteine-type endopeptidase inhibitor activity involved in apoptotic process; oxidoreductase activity; peroxidase activity; peroxiredoxin activity