Recombinant Human PPP2R1A Protein, Full Length, N-GST tagged
| Cat.No. : | PPP2R1A-49H |
| Product Overview : | Recombinant full-length human PPP2R1A was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
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| Description : | This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. |
| Source : | Sf9 insect cells |
| Species : | Human |
| Tag : | GST |
| Protein length : | Full Length |
| Molecular Mass : | 92 kDa |
| Purity : | The purity of PPP2R1A was determined to be > 70% by densitometry, approx. MW 92 kDa. |
| Stability : | One year at -70 centigrade from date of shipment. |
| Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Concentration : | 0.5 μg/μL |
| Storage Buffer : | 50mM Tris-HCl pH 7.5, 150mM NaCl,10mM glutathione, 0.1mM EDTA,0.25mMDTT, 0.1mM PMSF, 25% glycerol. |
| Shipping : | Dry ice |
| References : | 1. Tang Z, et al: PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation. Dev Cell. 10(5):575-85, 2006. |
| Gene Name | PPP2R1A protein phosphatase 2 scaffold subunit Aalpha [ Homo sapiens (human) ] |
| Official Symbol | PPP2R1A |
| Synonyms | PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha; HJS2; MRD36; PP2AA; PR65A; PP2AAALPHA; PP2A-Aalpha |
| Gene ID | 5518 |
| mRNA Refseq | NM_014225 |
| Protein Refseq | NP_055040 |
| MIM | 605983 |
| UniProt ID | P30153 |
Not For Human Consumption!
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