Recombinant Human PPP2CA Protein, Full Length, N-GST tagged

• Cat.No.: PPP2CA-50H
• Product Overview: Recombinant full-length human PP2A alpha was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: Full Length
• Description: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
• Molecular Mass: 59 kDa
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• References: 1. Van Hoof, C. et.al: Structure and chromosomal localization of the human gene of the phosphotyrosyl phosphatase activator (PTPA) of protein phosphatase 2A. Genomics 28: 261-272, 1995.
  2. Chao, Y. et.al: Structure and mechanism of the phosphotyrosyl phosphatase activator. Molec. Cell 23: 535-546, 2006.

Gene Information

• Gene Name: PPP2CA protein phosphatase 2 catalytic subunit alpha [ Homo sapiens (human) ]
• Official Symbol: PPP2CA
• Synonyms: PPP2CA; protein phosphatase 2 catalytic subunit alpha; HJS3; RP-C; PP2Ac; PP2CA; NEDLBA; PP2Calpha; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; protein phosphatase 2, catalytic subunit, alpha isozyme; replication protein C; EC 3.1.3.16; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; Names; medium tumor antigen-associated 61 KDA protein; protein phosphatase 2, regulatory subunit A, alpha; testicular secretory protein Li 1; EC 3.1.3.16; PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha; HJS2; MRD36; PP2AA; PR65A; PP2AAALPHA; PP2A-Aalpha
• Gene ID: 5515
• mRNA Refseq: NM_002715
• Protein Refseq: NP_002706
• MIM: 176915
• UniProt ID: P05323