Recombinant Human PPP1R16A Protein, MYC/DDK-tagged

• Cat.No.: PPP1R16A-2750H
• Product Overview: Recombinant Human PPP1R16A protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 57.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PPP1R16A protein phosphatase 1, regulatory subunit 16A [ Homo sapiens ]
• Official Symbol: PPP1R16A
• Synonyms: MYPT3; MYPT3
• Gene ID: 84988
• mRNA Refseq: NM_032902
• Protein Refseq: NP_116291
• MIM: 609172
• UniProt ID: Q96I34