Recombinant Human PPP1R14A, His-tagged

• Cat.No.: PPP1R14A-27586TH
• Product Overview: Recombinant Full Length human CPI17 alpha with His tag; 167 aa, 18kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Conjugation: HIS
• Tissue specificity: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris, 2mM EDTA, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSCGKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP
• Sequence Similarities: Belongs to the PP1 inhibitor family.
• Full Length: Full L.

Gene Information

• Gene Name: PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A [ Homo sapiens ]
• Official Symbol: PPP1R14A
• Synonyms: PPP1R14A; protein phosphatase 1, regulatory (inhibitor) subunit 14A; PPP1INL; protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC potentiated inhibitory protein of PP1; 17 KDa protein; CPI 17; PKC potentiated inhibitory protein of PP1
• Gene ID: 94274
• mRNA Refseq: NM_001243947
• Protein Refseq: NP_001230876
• MIM: 608153
• Uniprot ID: Q96A00
• Chromosome Location: 19q13.1
• Pathway: Vascular smooth muscle contraction, organism-specific biosystem; Vascular smooth muscle contraction, conserved biosystem
• Function: protein phosphatase inhibitor activity