Recombinant Human PPARA, GST-tagged

• Cat.No.: PPARA-113H
• Product Overview: Recombinant Human GST-tagged Peroxisome Proliferative Activated Receptor alpha ligand-binding domain (PPARα-LBD) consists of a 218 a.a. GST tag, a 14 a.a. flexible linker and a 292 a.a. PPARα-LBD, Acc# NP_001001928.1, amino acids 177-468, was produced in Sf9 insect cells infected with a recombinant baculovirus.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 177-468 a.a.
• Form: 20 mM Na-P pH 8.0, 40 mM KCl, 20 mM Na2MoO4, 7 mM reduced glutathione, 15% glycerol.
• Purity: >90%
• Applications: Ligand binding and coactivator peptide recruitment assays.
• Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.

Gene Information

• Gene Name: PPARA peroxisome proliferator-activated receptor alpha [ Homo sapiens ]
• Official Symbol: PPARA
• Synonyms: PPARA; peroxisome proliferator-activated receptor alpha; peroxisome proliferative activated receptor, alpha , PPAR; hPPAR; NR1C1; PPAR-alpha; nuclear receptor subfamily 1 group C member 1; peroxisome proliferative activated receptor, alpha; peroxisome proliferator-activated nuclear receptor alpha variant 3; PPAR; PPARalpha; MGC2237; MGC2452
• Gene ID: 5465
• mRNA Refseq: NM_001001928
• Protein Refseq: NP_001001928
• UniProt ID: Q07869
• Chromosome Location: 22q12-q13.1
• Pathway: Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian Repression of Expression by REV-ERBA, organism-specific biosystem; Developmental Biology, organism-specific biosystem
• Function: DNA binding; MDM2 binding; drug binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; lipid binding; metal ion binding; protein binding; protein domain specific binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; ubiquitin conjugating enzyme binding; zinc ion binding