Recombinant Human PPAN Protein, GST-His-tagged

• Cat.No.: PPAN-400H
• Product Overview: Recombinant Human PPAN fused with N-terminal GST and C-terminal His was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 79 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PPAN peter pan homolog (Drosophila) [ Homo sapiens (human) ]
• Official Symbol: PPAN
• Synonyms: SSF; SSF1; SSF2; BXDC3; SSF-1; PPAN
• Gene ID: 56342
• mRNA Refseq: NM_020230
• Protein Refseq: NP_064615
• MIM: 607793
• UniProt ID: Q9NQ55