Recombinant Human PORCN Protein (M1-G461 end, remove 219-228aa, C187A, A194S, K231G, R232T, K233M, A234V), GFP-Flag tagged

• Cat.No.: PORCN-0911H
• Product Overview: Recombinant Human PORCN(M1-G461 end) (remove 219-228aa) (C187A, A194S, K231G, R232T, K233M, A234V)-TEV-GFP-Flag Protein was expressed in Insect cell.

Specification

• Description: Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1), to Wnt proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors.
• Source: Insect cell
• Species: Human
• Tag: Flag&GFP
• Form: Liquid
• Protein length: M1-G461 end, remove 219-228aa, C187A, A194S, K231G, R232T, K233M, A234V
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 95%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 25 mM HEPES (pH 7.3), 300 mM NaCl, 4 mM DM, 0.1 mg/ml POPS.
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: PORCN porcupine O-acyltransferase [ Homo sapiens (human) ]
• Official Symbol: PORCN
• Synonyms: PORCN; porcupine O-acyltransferase; PPN; DHOF; FODH; MG61; PORC; protein-serine O-palmitoleoyltransferase porcupine; porcupine homolog; probable protein-cysteine N-palmitoyltransferase porcupine; EC 2.3.1.250
• Gene ID: 64840
• mRNA Refseq: NM_203475
• Protein Refseq: NP_982301
• MIM: 300651
• UniProt ID: Q9H237