Recombinant Human POLR2L, His-tagged

• Cat.No.: POLR2L-3056H
• Product Overview: Recombinant HumanPOLR2L (1-67 aa) is expressed inE.Coliwith a His tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-67 a.a.
• Description: POLR2L is a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
• MW: 7645 Da.
• Purity: 95%.
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. 10mM DTT.
• Application: MS. SDS.

Gene Information

• Gene Name: POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa [ Homo sapiens ]
• Synonyms: POLR2L; polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa; RBP10; RPB10; RPABC5; RPB7.6; hRPB7.6; hsRPB10b; RPB10beta; DNA directed RNA polymerase II polypeptide L; EC 2.7.7.6
• Gene ID: 5441
• mRNA Refseq: NM_021128
• Protein Refseq: NP_066951
• MIM: 601189
• UniProt ID: P62875
• Chromosome Location: 11p15
• Pathway: Huntington"s disease; Metabolic pathways; Purine metabolism; Pyrimidine metabolism; Gene Expression; HIV Infection; Regulatory RNA pathways; Transcription; mRNA Processing
• Function: DNA binding; DNA-directed RNA polymerase activity; metal ion binding; protein kinase activity; zinc ion binding