Recombinant Human PODXL Protein, His-tagged

• Cat.No.: PODXL-02H
• Product Overview: Recombinant Human PODXL Protein, fused to His-tag, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 23-429aa
• Description: This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
• Form: Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 43.1 kDa
• AA Sequence: SPSPSPS PSQNATQTTT DSSNKTAPTP ASSVTIMATD TAQQSTVPTS KANEILASVK ATTLGVSSDS PGTTTLAQQV SGPVNTTVAR GGGSGNPTTT IESPKSTKSA DTTTVATSTA TAKPNTTSSQ NGAEDTTNSG GKSSHSVTTD LTSTKAEHLT TPHPTSPLSP RQPTSTHPVA TPTSSGHDHL MKISSSSSTV AIPGYTFTSP GMTTTLPSSV ISQRTQQTSS QMPASSTAPS SQETVQPTSP ATALRTPTLP ETMSSSPTAA STTHRYPKTP SPTVAHESNW AKCEDLETQT QSEKQLVLNL TGNTLCAGGA SDEKLISLIC RAVKATFNPA QDKCGIRLAS VPGSQTVVVK EITIHTKLPA KDVYERLKDK WDELKEAGVS DMKLGDQGPP EEAEDRFSMP
• Endotoxin: < 1 EU per 1ug of protein (determined by LAL method).
• Purity: > 95%
• Applications: SDS-PAGE
• Notes: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: PODXL podocalyxin like [ Homo sapiens (human) ]
• Official Symbol: PODXL
• Synonyms: PODXL; Podocalyxin; Podocalyxin isoform 2; GCTM; GCTM-2 antigen; Gp200; Podocalyxin-like protein 1; PCLP; PCLP1; PCLP-1; Pcpodocalyxin; podocalyxin-like; PDX; gp135; PC; PODXL1
• Gene ID: 5420
• mRNA Refseq: NM_005397
• Protein Refseq: NP_005388.2
• MIM: 602632
• UniProt ID: O00592