Recombinant Human PNMA3 Protein, His-tagged

• Cat.No.: PNMA3-2412H
• Product Overview: Recombinant Human PNMA3 protein, fused to His-tagged at N-terminus, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 52.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PNMA3 paraneoplastic Ma antigen 3 [ Homo sapiens ]
• Official Symbol: PNMA3
• Synonyms: MA3; MA5
• Gene ID: 29944
• mRNA Refseq: NM_013364
• Protein Refseq: NP_037496
• MIM: 300675
• UniProt ID: Q9UL41