Recombinant Human PNLIP Protein, MYC/DDK-tagged

• Cat.No.: PNLIP-2415H
• Product Overview: Recombinant Human PNLIP protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the lipase family of proteins. The encoded enzyme is secreted by the pancreas and hydrolyzes triglycerides in the small intestine, and is essential for the efficient digestion of dietary fats. Inhibition of the encoded enzyme may prevent high-fat diet-induced obesity in mice and result in weight loss in human patients with obesity. Mutations in this gene cause congenital pancreatic lipase deficiency, a rare disorder characterized by steatorrhea.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 49.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PNLIP pancreatic lipase [ Homo sapiens ]
• Official Symbol: PNLIP
• Synonyms: PL; PNLIPD; PTL
• Gene ID: 5406
• mRNA Refseq: NM_000936
• Protein Refseq: NP_000927
• MIM: 246600
• UniProt ID: P16233