Recombinant Human PLIN3 protein, GST-tagged

• Cat.No.: PLIN3-321H
• Product Overview: Recombinant Human PLIN3(1 a.a. - 434 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 73.48 kDa
• AA Sequence: MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHVKTVCDAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGITEKAPEEKK
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Protein length: 1-434 a.a.

Gene Information

• Gene Name: PLIN3 perilipin 3 [ Homo sapiens ]
• Official Symbol: PLIN3
• Synonyms: PLIN3; perilipin 3; M6PRBP1, mannose 6 phosphate receptor binding protein 1; perilipin-3; cargo selection protein (mannose 6 phosphate receptor binding protein); MPR BINDING PROTEIN; 47 KD; placental protein 17; PP17; TIP47; 47 kDa MPR-binding protein; cargo selection protein TIP47; tail-interacting protein, 47 kD; mannose-6-phosphate receptor-binding protein 1; M6PRBP1; MGC2012; MGC11117
• Gene ID: 10226
• mRNA Refseq: NM_001164189
• Protein Refseq: NP_001157661
• MIM: 602702
• UniProt ID: O60664
• Chromosome Location: 19p13.3
• Function: protein binding