Recombinant Human PLEKHA1 protein, His & T7-tagged

• Cat.No.: PLEKHA1-1589H
• Product Overview: Recombinant Human PLEKHA1 aa. (Leu92~Glu346 (Accession # Q9HB21)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 32.5kDa
• Protein length: Leu92~Glu346
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 8.9

Gene Information

• Gene Name: PLEKHA1 pleckstrin homology domain containing A1 [ Homo sapiens (human) ]
• Official Symbol: PLEKHA1
• Synonyms: PLEKHA1; pleckstrin homology domain containing A1; TAPP1; pleckstrin homology domain-containing family A member 1; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1; tandem PH domain-containing protein 1
• Gene ID: 59338
• mRNA Refseq: NM_001001974.2
• Protein Refseq: NP_001001974.1
• UniProt ID: Q9HB21