Recombinant Human Pleiotrophin

• Cat.No.: PNT-1906H
• Product Overview: Recombinant humanfull length PNT is expressed in E. coli.

Specification

• Cat. No.: PNT-1906H
• Description: PNT and Midkine arestructurally related heparin-binding neurotrophic factors, whose expressionis developmentally regulated. The expression pattern of these neurotrophicfactors suggests function in neurogenesis, cell migration, secondary organogeneticinduction, and mesoderm epithelial interaction. The expression of PTN increasesduring the process of brain embryogenesis and reaches maximum levels at timeof birth.
• Source: E. coli
• Species: Human
• Form: Sterile filteredthrough a 0.2 micron filter. Lyophilized from 0.4x PBS, pH 7.2.
• Endotoxin Level: Less than 0.1 ng perμg (1 EU/μg).
• Purity: Greater than 98% bySDS-PAGE gel and HPLC analyses.
• Biological Activity: Data not availableat this time.
• Reconstitution: Centrifugevial prior to opening. Reconstitute in water to a concentrationof 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffersand stored at 4°C for 1 week or -20°C for future use.
• Storage: Thelyophilized protein is stable for a few weeks at room temperature, but beststored at -20°C. Reconstituted Pleiotrophin should be stored in workingaliquots at -20°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: PTN
• Tag: Non
• Full Length: Full L.

Gene Information

• Gene Name: PTN pleiotrophin [ Homosapiens ]
• Synonyms: PTN; pleiotrophin; HARP; HBNF;HBGF8; NEGF1; PTN; Heparin-binding growth-associated molecule; HB-GAM;Heparin-binding growth factor 8;Osteoblast-specific factor 1; OSF-1; Heparin-binding neuriteoutgrowth-promoting factor 1; HBNF-1; Heparin-binding brain mitogen; HBBM;HBGF-8; HBNF1; heparin affin regulatory protein; heparin binding growth factor8; neurite growth-promoting factor 1
• Gene ID: 5764
• mRNA Refseq: NM_002825
• Protein Refseq: NP_002816
• MIM: 162095
• UniProt ID: P21246
• Chromosome Location: 7q33-q34
• Pathway: Syndecan-3-mediated signaling events
• Function: growth factor activity; heparinbinding; phosphoprotein phosphatase inhibitor activity