Recombinant Human PLD3, MYC/DDK-tagged

• Cat.No.: PLD3-106H
• Product Overview: Recombinant Human phospholipase D family, member 3 (PLD3), transcript variant 1, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Molecular Mass: 54.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: PLD3 phospholipase D family, member 3 [ Homo sapiens (human) ]
• Official Symbol: PLD3
• Synonyms: PLD3; HUK4; HU-K4; phospholipase D family, member 3; hospholipase D3; PLD 3; hindIII K4L homolog; choline phosphatase 3; phosphatidylcholine-hydrolyzing phospholipase D3; NP_001026866.1; EC 3.1.4.4; NP_036400.2
• Gene ID: 23646
• mRNA Refseq: NM_001031696
• Protein Refseq: NP_001026866
• MIM: 615698
• UniProt ID: Q8IV08
• Chromosome Location: 19q13.2
• Pathway: Ether lipid metabolism; Glycerophospholipid biosynthesis; Phospholipid metabolism
• Function: N-acylphosphatidylethanolamine-specific phospholipase D activity; phospholipase D activity; protein binding