Recombinant Human PLD3, GST-tagged

• Cat.No.: PLD3-105H
• Product Overview: Recombinant Human PLD3(1 a.a. - 490 a.a.) , fused with GST-tag at N-terminal, was expressed in wheat germ.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Molecular Mass: 81.1 kDa
• AA Sequence: MKPKLMYQELKVPAEEPANELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRPA PCYDPCEAVLVESIPEGLDFPNASTGNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQGEEVLRQ LQTLAPKGVNVRIAVSKPSGPQPQADLQALLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYLGSANMDWRSLT QVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRFYDTRYNQETPMEICLNGTPALAYLASAPPPLC PSGRTPDLKALLNVVDNARSFIYVAVMNYLPTLEFSHPHRFWPAIDDGLRRATYERGVKVRLLISCWGHSEPSMR AFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERATYIGTSNWSGNYFTETAGTSLLVTQ NGRGGLRSQLEAIFLRDWDSPYSHDLDTSADSVGNACRLL
• Applications: ELISA; WB-Re; AP; Array
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: PLD3 phospholipase D family, member 3 [ Homo sapiens (human) ]
• Official Symbol: PLD3
• Synonyms: PLD3; HUK4; HU-K4; phospholipase D family, member 3; hospholipase D3; PLD 3; hindIII K4L homolog; choline phosphatase 3; phosphatidylcholine-hydrolyzing phospholipase D3; NP_001026866.1; EC 3.1.4.4; NP_036400.2
• Gene ID: 23646
• mRNA Refseq: NM_001031696
• Protein Refseq: NP_001026866
• MIM: 615698
• UniProt ID: Q8IV08
• Chromosome Location: 19q13.2
• Pathway: Ether lipid metabolism; Glycerophospholipid biosynthesis; Phospholipid metabolism
• Function: NAPE-specific phospholipase D activity; phospholipase D activity; protein binding