Recombinant Human PLA2G7 Protein, His-tagged

• Cat.No.: PLA2G7-089H
• Product Overview: Active recombinant N-terminal hexahistidine-tagged full length human PLA2G7 protein (42-441) was expressed in E. coli

Specification

• Description: The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 46.4 kDa
• Protein length: 42-441
• Purity: ≥85% estimated by SDS-PAGE
• Unit Definition: One unit is defined as the amount of enzyme required to produce 1 μmol of TNB per minute at 37 centigrade in buffer containing 100mM Tris-HCl, pH7.2, and 300 μM of the substrate 2-thio PAF.
• Stability: ≥ 2 year
• Storage: At -80 centigrade.
• Storage Buffer: 50 mM sodium phosphate pH 7.2, 100 mM NaCl, 20% glycerol

Gene Information

• Gene Name: PLA2G7 phospholipase A2 group VII [ Homo sapiens (human) ]
• Official Symbol: PLA2G7
• Synonyms: PLA2G7; phospholipase A2 group VII; PAFAD; PAFAH; LP-PLA2; LDL-PLA2; platelet-activating factor acetylhydrolase; 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; LDL-PLA(2); LDL-associated phospholipase A2; PAF 2-acylhydrolase; PAF acetylhydrolase; gVIIA-PLA2; group-VIIA phospholipase A2; lipoprotein-associated phospholipase A2; phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma); EC 3.1.1.47
• Gene ID: 7941
• mRNA Refseq: NM_005084
• Protein Refseq: NP_005075
• MIM: 601690
• UniProt ID: Q13093