PLA2G7
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Official Full Name
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -
Overview
The PLA2G7 gene encodes platelet-activating factor (PAF) acetylhydrolase (EC 3.1.1.47), a secreted enzyme that catalyzes the degradation of PAF to inactive products by hydrolysis of the acetyl group at the sn-2 position, producing the biologically inactive products LYSO-PAF and acetate. -
Synonyms
PLA2G7;phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma);platelet-activating factor acetylhydrolase;LDL PLA2;PAFAH;LDL-PLA(2);gVIIA-PLA2;PAF 2-acylhydrolase;PAF acetylhydrolase;group-VIIA phospholipase A2;LDL-associated phospholipase A2;lipoprotein-associated phospholipase A2;1-alkyl-2-acetylglycerophosphocholine esterase;2-acetyl-1-alkylglycerophosphocholine esterase;PAFAD;LP-PLA2;LDL-PLA2
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Dog
- Rat
- HEK293
- E.coli
- Wheat Germ
- Mammalian Cell
- Human
- CHO
- Human Cell
- HEK293F
- Mammalian cells
- Insect Cell
- His
- Non
- GST
- His&Flag
- Flag
- His&GST
- His&SUMO
- His&Myc
- His&Fc&Avi
Involved Pathway
PLA2G7 involved in several pathways and played different roles in them. We selected most pathways PLA2G7 participated on our site, such as Ether lipid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ether lipid metabolism | PPAP2C,PLD2,PLA2G2A,PAFAH1B2,PLA2G2F,PLA2G10,PPAP2A,PLA2G4B,PPAP2B,PAFAH1B1 |
| Metabolic pathways | NOS3,CBS,CERS4,PKM2,MDH2,EPT1,ZNF408,HGD,NOS1,LCT |
Protein Function
PLA2G7 has several biochemical functions, for example, 1-alkyl-2-acetylglycerophosphocholine esterase activity,calcium-independent phospholipase A2 activity,phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G7 itself. We selected most functions PLA2G7 had, and list some proteins which have the same functions with PLA2G7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 1-alkyl-2-acetylglycerophosphocholine esterase activity | ASPG,PAFAH2,PAFAH1B3,PAFAH1B2 |
| phospholipid binding | PACSIN1,APOEB,MTAP1B,SGIP1,TEC,ABCA1,SHC1,HIP1RB,PON1,SDPR |
| calcium-independent phospholipase A2 activity | PLA2G15,PNPLA8,PLA2G4C |
Interacting Protein
PLA2G7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G7 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G7.
metE;fadH;ESR1
Resources
Research Area
Enzymes Secreted by Endothelial CellsInflammatory Mediators
Fatty Acid Catabolism
Other Secreted VSMC Molecules
Related Services
Related Products
References
