Recombinant Human PLA2G5, His-tagged
| Cat.No. : | PLA2G5-31349TH |
| Product Overview : | Recombinant mature full length protein, corresponding to amino acids 21-138 of the Human Secretory phospholipase A2 Type V precursor , with a 16 amino acid N-terminal His tag.134 amino acids in total. |
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| Description : | This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. |
| Conjugation : | HIS |
| Source : | E. coli |
| Tissue specificity : | Heart, placenta and less abundantly, in lung. |
| Form : | Liquid |
| Purity : | >95% by SDS-PAGE |
| Storage buffer : | Preservative: None0.05M Acetate buffer pH 4.0 |
| Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
| Sequences of amino acids : | MRGSHHHHHH GMASHMGLLD LKSMIEKVTG KNALTNYGFYGCYCGWGGRG TPKDGTDWCC WAHDHCYGRL EEKGCNIRTQSYKYRFAWGV VTCEPGPFCH VNLCACDRKL VYCLKRNLRSYNPQYQYFPN ILCS |
| Sequence Similarities : | Belongs to the phospholipase A2 family. |
| Protein length : | 21-138 a.a. |
| Full Length : | Full L. |
| Gene Name | PLA2G5 phospholipase A2, group V [ Homo sapiens ] |
| Official Symbol | PLA2G5 |
| Synonyms | PLA2G5; phospholipase A2, group V; calcium-dependent phospholipase A2; |
| Gene ID | 5322 |
| mRNA Refseq | NM_000929 |
| Protein Refseq | NP_000920 |
| MIM | 601192 |
| Uniprot ID | P39877 |
| Chromosome Location | 1p36-p34 |
| Pathway | Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Ether lipid metabolism, organism-specific biosystem; Ether lipid metabolism, conserved biosystem; Fat digestion and absorption, organism-specific biosystem; |
| Function | calcium ion binding; calcium-dependent phospholipase A2 activity; heparin binding; hydrolase activity; |
Not For Human Consumption!
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